AcuPlus Ingredients: What’s Inside Our Menthol Pain Relief Cream

AcuPlus Pain Relief Cream is a topical pain relief formula made for targeted, everyday muscle and joint comfort. The active ingredient is menthol 3.5%, a topical analgesic that creates a cooling sensation on the skin to help temporarily relieve minor aches and pains.


In addition to menthol, AcuPlus includes a comfort-focused blend of supportive ingredients such as aloe vera, arnica, MSM, magnesium sulfate, boswellia serrata, glucosamine sulfate, willow bark, vitamin B6, vitamin E, licorice root, ilex, and cetyl myristoleate.


AcuPlus is designed for people who want a topical option they can apply directly to areas such as the back, neck, shoulders, knees, hands, wrists, feet, and other sore muscle and joint areas.

AcuPlus Ingredient Blend

Supportive Ingredients in the AcuPlus Formula

These ingredients help support the overall AcuPlus topical experience, including skin feel,massage-in application, comfort, hydration, and formula performance.

1

Skin Feel + Hydration

Ingredients selected to help support a soothing, conditioned feel on the skin.

  • Aloe Vera

    Helps support a soothing, hydrating skin feel.

  • Vitamin E

    Helps condition the skin and support the feel of the formula.

  • Licorice Root Extract

    A botanical extract often used in skin-care and comfort-focused formulas.

2

Massage-In Comfort Support

Ingredients commonly used in topical body-care and muscle comfort formulas.

  • Arnica Montana Flower Extract

    A botanical ingredient traditionally used in topical body-care formulas.

  • MSM

    A sulfur-containing ingredient commonly used in topical muscle and joint comfort formulas.

  • Magnesium Sulfate

    A mineral ingredient often used in body-care and bath-care products.

3

Joint-Care Inspired Ingredients

Ingredients commonly associated with joint-care and wellness formulas.

  • Boswellia Serrata Extract

    A botanical extract commonly associated with joint-care and wellness formulas.

  • Glucosamine Sulfate

    A well-known ingredient often included in joint-support formulas.

  • Willow Bark Extract

    A botanical extract traditionally used in wellness and body-care products.

4

Supportive Formula Blend

Ingredients included as part of the complete AcuPlus formula blend.

  • Vitamin B6

    Also called pyridoxine; included as part of the supportive formula blend.

  • Ilex Paraguariensis Extract

    A botanical extract included as part of the AcuPlus ingredient blend.

  • Cetyl Myristoleate / CMO

    A fatty acid ester included in the formula blend.

Menthol is the active ingredient in AcuPlus topical pain relief products. The ingredients listed above are supportive ingredients included to help create the overall topical experience, skin feel, massage-in application, and formula performance.

Active Ingredient: Menthol 3.5%

Menthol is the active ingredient in AcuPlus Pain Relief Cream. It is listed as a topical analgesic, which means it is used on the skin to help temporarily relieve minor aches and pains.


Menthol creates a cooling sensation that helps distract from discomfort in sore muscles and joints. This makes AcuPlus a convenient topical option for everyday aches associated with simple backache, arthritis, strains, bruises, and sprains.


Why it matters:

Menthol gives AcuPlus its recognizable cooling feel and helps provide targeted temporary relief where the product is applied.

Menthol creates a sensation that overrides pain signals to the brain. This process is known as the ‘Gate Control Theory’, where nerve impulses from one stimulus block the nerves containing pain signals to the brain. Recent research also suggests that menthol may stimulate cold receptors in the skin that may help regulate pain as well. This is known as ‘cold therapy,’ or cryotherapy. Cryotherapy is the application of cold to temporarily relieve pain. The most common form of cryotherapy is ice. AcuPlus produces the same sensation of cold that accompanies icing but without the pain and numbness sometimes associated with ice. Best of all, AcuPlus products allow you to remain active during treatment. 

ARNICA

Arnica Montana, a plant native to mountainous areas of Europe and North America, has been used for centuries to treat a variety of pain. Arnica works by stimulating the activity of white blood cells responsible for the digestion of congested blood, and by moving trapped fluids from bruised tissue, joints, and muscle. Several published studies have shown the benefits of Arnica in treating osteoarthritis with significant reductions in pain and stiffness.

BOSWELLIA SERRATA

Boswellia Serrata is an all natural extract from a tree grown in dry, mountainous regions in India, Northern Africa, and the Middle East. It has been found to be so effective at reducing inflammation that it’s even being deemed as a promising alternative to prescription anti-inflammatories. There are several double blind, placebo-controlled, randomized studies showing both clinical and statistical significant improvements in pain and function in people with arthritis.

MSM

MSM or methylsulfonylmethane, is an organic form of sulfur. It has the remarkable ability to restore flexibility and permeability to cell walls, allowing fluids to pass through tissues with ease so medication can absorb more easily. It is also a powerful detoxifier moving lactic acid and toxins out of cells helping equalize pressure in muscles and joints. It’s even used on racehorses before and after a race to prevent soreness and reduce the risk of cramping.

CMO

CMO or Cetyl myristoleate is a natural fatty acid. CMO was initially isolated in studies performed at the National Institutes of Health when it was found that high concentrations of CMO protected subjects from developing experimentally-induced arthritis. CM is frequently used in oral and topical applications to help relieve joint pain and reduce further joint damage thought to be caused by inflammation.

GLUCOSAMINE

Glucosamine is an all natural compound found in your body that helps keep up the health of your cartilage. As we age levels of this compound drop and there are studies suggesting the use of glucosamine can help counteract this effect. The natural anti-inflammatory and anti-aging properties of glucosamine are frequently used by people trying to relieve bone and joint pain.

MAGNESIUM

Transdermal magnesium is one of the most popular and fast-acting ways to get the benefits of magnesium. Topical magnesium has been used for centuries as a treatment for sore muscles, pain, cramping, and Restless Leg Syndrome. In addition to these pain relieving properties additional documented benefits from magnesium include better sleep and relief from stress.

VITAMIN B-6

Vitamin B6, also called pyridoxine, is involved in the process of making serotonin and norepinephrine, which are chemicals that transmit signals to the brain. Vitamin B6 is also involved in the formation of myelin, a protein layer that forms around nerve cells. Vitamin B6 is commonly used to help prevent and treat nerve inflammation.

WILLOW BARK

Willow Bark’s pain relieving potential has been recognized throughout history going back to the time of Hippocrates. The active ingredient in the medicine made from willow bark is called salicin. Willow bark is often used as an alternative to aspirin, particularly those that experience muscle pain or pain related to arthritis.

ALOE VERA

Aloe vera is considered to be the most biologically active of the aloe species and contains the antioxidant vitamins A, C, B12, folic acid, and choline. Aloe vera’s amazing number of vitamins and minerals have been shown to help reduce inflammation and fight free radical damage. It is also well known for its ability to protect and hydrate the skin.

ILEX

Ilex, an herbal extract from a South American holly shrub, has been employed for centuries as an herbal remedy. The primary active ingredient in holly is caffeine which helps promote circulation. Ilex was used traditionally by Paraguayan Indians to enhance the effectiveness of their medicines, and today is incorporated into various preparations worldwide to enhance health and wellness.

VITAMIN E

Vitamin E acts as an antioxidant, helping protect the body from free radicals, which are compounds that can damage the body. Several studies suggest that Vitamin E may be helpful in pain management for several conditions, including nerve pain.

LICORICE ROOT

Licorice Root has been used for centuries by the Egyptians, Chinese, Greek and many other nations in Asia as a natural muscle relaxer and topical anti-inflammatory as it acts similar to hydrocortisone. It’s anti-inflammatory benefits have also been used as a natural remedy for joint pain and tendonitis.

Topical Comfort

How AcuPlus Supports Targeted Muscle and Joint Comfort

AcuPlus is made for people who want to apply topical relief directly where they feel everyday soreness.It is applied to the skin and massaged into the area where temporary relief is needed.

Designed for direct application

Apply comfort where you need it most.

AcuPlus gives you a topical option for minor muscle and joint aches. Instead of a one-size-fits-all routine,you can apply it directly to areas like the back, neck, shoulders, knees, wrists, hands, feet, and legs.

Use at home after long days.
Apply after activity or movement.
Add to your daily comfort routine.
1

Targeted

Apply AcuPlus directly to sore muscles and joints where temporary relief is needed.

2

Cooling

Menthol creates the cooling sensation people feel after applying AcuPlus to the skin.

3

Fast-Absorbing

The cream massages in smoothly and is designed to absorb without a heavy, greasy feel.

4

Convenient

Use AcuPlus at home, after activity, after long days, or as part of your regular comfort routine.

5

Comfort-Focused

AcuPlus combines menthol with a broad supportive ingredient blend for a complete topical experience.

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Topical First

A simple option for people who prefer applying relief directly to the area of everyday soreness.

AcuPlus Pain Relief Cream contains menthol 3.5% as the active ingredient for temporary relief of minor aches and pains of muscles and joints. Always read and follow the product label directions.
ACUPLUS MANUFACTURING PROCESS

AcuPlus is manufactured in small batches at a state-of-the-art 90,000-square-foot facility that is UL-certified, FDA-Certified, and QAI-certified organic. 


Each batch is produced using high-quality ingredients, modern manufacturing technology, and strict quality-control procedures.


Throughout the manufacturing process, every batch is carefully reviewed by qualified chemists and supervised by trained production professionals before moving to the packaging line. Batches are also sent to independent laboratories for additional testing to verify active ingredient strength and check for microbiological content in accordance with FDA guidelines.


AcuPlus is routinely inspected during both manufacturing and packaging to help maintain product consistency, accurate fill weights, and proper packaging quality. This process helps ensure that every jar and roll-on meets the standards customers and wellness professionals expect from AcuPlus.

Ingredient FAQs

Frequently Asked Questions About AcuPlus Ingredients

Learn more about the active ingredient in AcuPlus Pain Relief Cream and the supportive ingredients included in the AcuPlus topical formula.

1

What is the active ingredient in AcuPlus Pain Relief Cream?

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The active ingredient in AcuPlus Pain Relief Cream is menthol 3.5%. Menthol is a topical analgesic used to help temporarily relieve minor aches and pains of sore muscles and joints.

Active ingredient
2

Is menthol the ingredient that gives AcuPlus its cooling feel?

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Yes. Menthol creates the cooling sensation people feel after applying AcuPlus to the skin.

Cooling sensation
3

Does AcuPlus contain arnica?

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Yes. AcuPlus includes Arnica Montana Flower Extract as part of its supportive ingredient blend.

Botanical ingredient
4

Does AcuPlus contain magnesium?

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Yes. AcuPlus includes magnesium sulfate as one of its supportive ingredients.

Mineral ingredient
5

Does AcuPlus contain MSM?

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Yes. AcuPlus includes methylsulfonylmethane, commonly known as MSM.

Supportive ingredient
6

Is AcuPlus greasy?

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AcuPlus is designed to massage into the skin smoothly and absorb without a heavy, greasy feel.

Skin feel
7

Where can I apply AcuPlus?

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AcuPlus can be applied to sore muscle and joint areas such as the back, neck, shoulders, knees, wrists, hands, feet, and legs. Always follow the product label directions.

How to use
AcuPlus Pain Relief Cream contains menthol 3.5% as the active ingredient. Supportive ingredients are included to help create the overall topical experience, skin feel, massage-in application, and formula performance.
Directions + Safety

How to Use AcuPlus

Use AcuPlus as directed for temporary relief of minor aches and pains of muscles and joints. Apply a thin layer, massage into the skin, and always follow the product label directions.

Step-by-Step Application

A simple guide for applying AcuPlus Pain Relief Cream or Roll-On to sore muscle and joint areas.

  1. 1

    Choose the area

    Apply AcuPlus to sore muscle or joint areas such as the back, neck, shoulders, knees, wrists, hands, feet, or legs.

  2. 2

    Use a thin layer

    Apply only a thin layer to the affected area. More product is not always better.

  3. 3

    Massage in gently

    Massage into the skin until absorbed. AcuPlus is designed to go on smoothly without a heavy, greasy feel.

  4. 4

    Use up to 3 times daily

    Adults and children 2 years of age and older may apply to the affected area up to 3 times daily, or as directed on the product label.

  5. 5

    Wash hands after use

    After applying, wash hands with cool water unless you are treating the hands. Avoid touching your eyes after application.

For external use only. AcuPlus Pain Relief Cream contains menthol 3.5% as the active ingredient. Always read and follow the product label before use.
Shop AcuPlus Pain Relief

Choose the AcuPlus Product That Fits Your Routine

Whether you prefer a massage-in cream or a hands-free roll-on, AcuPlus gives you targeted topical comfort for everyday muscle and joint aches.

AcuPlus Pain Relief Cream and Roll-On contain menthol as the active ingredient for temporary relief of minor aches and pains of muscles and joints. Always read and follow the product label directions.

Full AcuPlus Ingredient List:


Active Ingredient:

Menthol 3.5% — Topical Analgesic


Other Ingredients:

Aloe Barbadensis Leaf Juice, Aqua, Arnica Montana Flower Extract, Boswellia Serrata Extract, Carbomer, Cetyl Myristoleate, Ethylhexylglycerin, Glucosamine Sulfate, Glycyrrhiza Glabra Root Extract, Ilex Paraguariensis Extract, Isopropyl Alcohol, Magnesium Sulfate, Melaleuca Alternifolia Oil, Methylsulfonylmethane, Phenoxyethanol, Polysorbate-20, Pyridoxine HCl, Salix Alba Bark Extract, Tetrasodium EDTA, Tocopheryl Acetate, Triethanolamine.